JMJD6 (N-terminus) monoclonal Antibody | MB0100

JMJD6 (N-terminus) monoclonal Antibody | MB0100 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Application: WB ICC

Application Range: WB: 1:1000 ICC: 1:100~200

Background: Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of JMJD6 and does not cross-react with related proteins

Molecular Weight: Predicted band size:46KDa Observed band size:62KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PSR; PTDSR; PTDSR1; KIAA0585; jumonji domain containing 6; Lysyl-hydroxylase JMJD6; Phosphatidylserine receptor; PTDSR; KIAA0585; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; PSR; Peptide-lysine 5-dioxygenase JMJD6; Protein PTDSR

Immunogen: Synthetic peptide, corresponding to the N-terminus of Human JMJD6.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Dopamine Signaling in Parkinson's Disease Plathway,