K-7174 dihydrochloride | 9478

K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α. K7174 also ameliorated anemia induced by inflammatory cytokines in mice.

K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α. K7174 also ameliorated anemia induced by inflammatory cytokines in mice.

9478 | K-7174 dihydrochloride DataSheet

Alternate Name/Synonyms: 1,4-bis((E)-5-(3,4,5-trimethoxyphenyl)pent-4-en-1-yl)-1,4-diazepane dihydrochloride

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 191089-60-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₃₃H₅₀BrCl₂N₂O6

Molecular Weight: 641.67

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>6 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A novel cell adhesion inhibitor

MDL Number: N/A

PubChem CID: N/a

SMILES: COC1=C(OC)C(OC)=CC(/C=C/CCCN2CCN(CCC/C=C/C3=CC(OC)=C(OC)C(OC)=C3)CCC2)=C1.[H]Cl.[H]Cl

InChi: InChI=1S/C33H48N2O6.2ClH/c1-36-28-22-26(23-29(37-2)32(28)40-5)14-9-7-11-16-34-18-13-19-35(21-20-34)17-12-8-10-15-27-24-30(38-3)33(41-6)31(25-27)39-4;;/h9-10,14-15,22-25H,7-8,11-13,16-21H2,1-6H3;2*1H/b14-9+,15-10+;;

InChi Key: JKAQFPBRMVEHBD-CHBZAFCASA-N