kb NB 142-70 | 9566

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC₅₀ values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively. More potent analog of CID-755673 (Cat.No. 2660) with 7-fold greater inhibition. Inhibits prostate cancer cell migration and invasion and reduces wound healing in vitro; displays prominent cytotoxic and anti-proliferative effects.

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC₅₀ values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively. More potent analog of CID-755673 (Cat.No. 2660) with 7-fold greater inhibition. Inhibits prostate cancer cell migration and invasion and reduces wound healing in vitro; displays prominent cytotoxic and anti-proliferative effects.

9566 | kb NB 142-70 DataSheet

Alternate Name/Synonyms: 9-Hydroxy-3,4-dihydro-2H-[1]-benzothiolo[2,3-f][1,4]thiazepin-5-one

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1233533-04-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₉NO₂S₂

Molecular Weight: 251.32

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective protein kinase D (PKD) inhibitor

MDL Number: MFCD18086915

PubChem CID: 45258277

SMILES: C1CSC2=C(C(=O)N1)SC3=C2C=C(C=C3)O

InChi: InChI=1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14)

InChi Key: DHUAGGSHTKPOHU-UHFFFAOYSA-N