KBTBD3 polyclonal Antibody | BS6807

KBTBD3 polyclonal Antibody | BS6807 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KBTBD3 polyclonal Antibody detects endogenous levels of KBTBD3 protein.

Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BKLHD3; BTB and kelch domain-containing protein 3; Kelch repeat and BTB domain-containing protein 3;

Immunogen: Recombinant full length Human KBTBD3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: