KCNAB1 Antibody | 15-994

KCNAB1 Antibody | 15-994 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 282-401 of human KCNAB1 (NP_751891.1) .

Research Area: Neuroscience

Tested Application: WB

Application: WB: 1:200 - 1:2000

Specificiy: N/A

Positive Control 1: U-251MG

Positive Control 2: 293T

Positive Control 3: Mouse brain

Positive Control 4: Mouse kidney

Positive Control 5: Mouse heart

Positive Control 6: Rat brain

Molecular Weight: Observed: 45-50kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: KCNAB1, hKvb3, AKR6A3, KCNA1B, Kvb1.3, hKvBeta3, KV-BETA-1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alpha subunits.