KCNK1 Antibody | 8017

KCNK1 Antibody | 8017 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Rabbit: (100%) , Bovine: (100%) , Guinea pig: (100%)

Immunogen: KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1.
The immunogen is located within amino acids 220 - 270 of KCNK1.

Research Area: Neuroscience

Tested Application: E, WB, IHC-P, IF

Application: KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Specificiy: KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.

Positive Control 1: Cat. No. 1212 - 3T3 Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 37 kDa
Observed: 35 kDa

Validation: N/A

Isoform: N/A

Purification: KCNK1 antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: KCNK1 antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: KCNK1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: Potassium channel subfamily K member 1, DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The potassium channel, subfamily K, member 1 (KCNK1) , is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1, 2) . KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1) . Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3) .