KCNMB2 Antibody (C-term) [APR33158G]

KCNMB2 Antibody (C-term) [APR33158G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This KCNMB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 174-189 amino acids from the C-terminal region of human KCNMB2.

Cellular Localisation: Membrane; Multi-pass membrane protein.

Molecular Weight: 27130

Clone: Polyclonal

Gene Name: KCNMB2

Gene ID: 10242

Function: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons.

Summary: Tissue Location: Expressed in kidney, heart and brain. Highly expressed in ovary. Expressed at low level in other tissues

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000 WB--1:1000

Synonyms: Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Hbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K (VCA) beta-2, Maxi K channel subunit beta-2, Slo-beta-2, KCNMB2