KCNQ5 Antibody | 16-449

KCNQ5 Antibody | 16-449 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 624-923 of human KCNQ5 (NP_001153602.1) .

Research Area: Neuroscience

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: A-549

Positive Control 3: Mouse brain

Positive Control 4: Mouse lung

Positive Control 5: Rat brain

Positive Control 6: N/A

Molecular Weight: Observed: 102kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: potassium channel protein, OTTHUMP00000064153, OTTHUMP00000064152, OTTHUMP00000016729, Kv7.5, potassium voltage-gated channel, KQT-like subfamily, member 5, KCNQ5

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene.