KDM4C Polyclonal Antibody | E-AB-13351

KDM4C Polyclonal Antibody | E-AB-13351 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: bA146B14.1, GASC 1 protein, GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain containing histone demethylation protein 3C, JmjC domain-containing histone demethylation protein 3C, JMJD2C, Jumonji domain containing 2C, Jumonji domain containing protein 2C, Jumonji domain-containing protein 2C, Kdm4c, KDM4C, Lysine (K) specific demethylase 4C, Lysine demethylase 4C, Lysine-specific demethylase 4C, TDRD14C, Tudor domain containing 14C

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human KDM4C

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 120 kDa

Molecular Weight(Observed): N/A