Ketorolac | B2170

Ketorolac is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic, and antipyretic activities. Ketorolac non-selectively inhibits the enzymes COX-1 and COX-2. The inhibition of COX-2, up-regulated at sites of inflammation, prevents conversion of arachidonic acid to pro-inflammatory prostaglandins.

Ketorolac is a synthetic pyrrolizine carboxylic acid derivative with anti-inflammatory, analgesic, and antipyretic activities. Ketorolac non-selectively inhibits the enzymes COX-1 and COX-2. The inhibition of COX-2, up-regulated at sites of inflammation, prevents conversion of arachidonic acid to pro-inflammatory prostaglandins.

B2170 | Ketorolac DataSheet

Alternate Name/Synonyms: 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; Ketorolaco; Ketorolacum

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 74103-06-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₃NO₃

Molecular Weight: 255.27

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A cyclooxygenase (COX) inhibitor

MDL Number: MFCD00864281

PubChem CID: 3826

SMILES: C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O

InChi: InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)

InChi Key: OZWKMVRBQXNZKK-UHFFFAOYSA-N