KG-501 | B2380

KG-501 is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM).

KG-501 is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM).

B2380 | KG-501 DataSheet

Alternate Name/Synonyms: Naphthol AS-E phosphate, [3-[(4-chlorophenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate, N-(4-Chlorophenyl)-3-(phosphonooxy)naphthalene-2-carboxamide

Appearance: Off-white solid

Formulation:

CAS Number: 18228-17-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₇H₁₃ClNO₅P

Molecular Weight: 377.72

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: >5 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A cAMP response element-binding protein (CREB) inhibitor

MDL Number: MFCD00042718

PubChem CID: 87517

SMILES: ClC(C=C1)=CC=C1NC(C2=CC3=CC=CC=C3C=C2OP(O)(O)=O)=O

InChi: InChI=1S/C17H13ClNO5P/c18-13-5-7-14(8-6-13)19-17(20)15-9-11-3-1-2-4-12(11)10-16(15)24-25(21,22)23/h1-10H,(H,19,20)(H2,21,22,23)

InChi Key: RQAQWBFHPMSXKR-UHFFFAOYSA-N