Ki 16425 | 9545

Ki 16425 is a LPA (Lysophosphatidic acid) receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells.

Ki 16425 is a LPA (Lysophosphatidic acid) receptor antagonist with selectivity for LPA1 and LPA3. It exhibits Ki values of 0.34, 6.5, and 0.93 µM for the human LPA1, LPA2, and LPA3 receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells.

9545 | Ki 16425 DataSheet

Alternate Name/Synonyms: 3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid

Appearance: Off-white solid

Formulation: N/A

CAS Number: 355025-24-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₃ClN₂O₅S

Molecular Weight: 474.96

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml) or EtOH (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A LPA (Lysophosphatidic acid) receptor antagonist

MDL Number: MFCD06798341

PubChem CID: 10367662

SMILES: CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)O

InChi: InChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28)

InChi Key: LLIFMNUXGDHTRO-UHFFFAOYSA-N