Kif 7 Monoclonal Antibody | ABM40063

Kif 7 Monoclonal Antibody | ABM40063 | Gentaur UK, US & Europe Distribution

Immunogen: Synthetic Peptide

Product Category: Protein

Application: Protein General Reagents

Product Type: Primary Antibody

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC-P, IF

Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:100-1:200), IHC-P (1:200) .

Clonality: Monoclonal

Isotype: Mouse IgG1

Formulation: Liquid solution

Kit Component: N/A

Concentration: 1 mg/ml

Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Shipping Condition: Gel pack with blue ice.

Background: KIF7 encodes a cilia-associated protein (kinesin family member 7) belonging to the kinesin family. Kinesin family member 7 plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in KIF7 have been associated with various ciliopathies.

Alternative Names: N/A

Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.