KIF7 Monoclonal Antibody | E-AB-22026

KIF7 Monoclonal Antibody | E-AB-22026 | Gentaur UK, US & Europe Distribution

Type: Monoclonal Antibody

Synonyms: EQYK340, kif7, KIF7, kinesin family member 7, kinesin like protein KIF7, Kinesin-like protein kif7, UNQ340

Application: IHC-p, IF

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Reserch Areas: Signal Transduction, Stem Cells

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.KIF7 (Kinesin Family Member 7) is a Protein Coding gene. Diseases associated with KIF7 include Acrocallosal Syndrome and Hydrolethalus Syndrome 2. Among its related pathways are Signaling by Hedgehog and Signaling by GPCR. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF27.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: IHC 1:100-1:300, IF 1:50-200

Clone: Clone:3I4

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A