KIRREL Antibody (C-term) [APR17029G]

KIRREL Antibody (C-term) [APR17029G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm

Molecular Weight: 83536

Clone: Polyclonal

Gene Name: KIRREL1 (HGNC:15734)

Gene ID: 55243

Function: Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity) .

Summary: Tissue Location: Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1