KLK6 Polyclonal Antibody | E-AB-40296

KLK6 Polyclonal Antibody | E-AB-40296 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Kallikrein related peptidase 6, Klk-8, Klk8, Kallikrein-6, KLK 6, MGC9355, mGK 1, mGK1, MSP, PRSS 18, PRSS 9

Application: IHC, IF

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Neuroscience, Signal Transduction

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Rat Prostatic glandular kallikrein-6 protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Antigen Affinity Purification

Dilution: IHC 1:100-1:300 IF 1:100-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A