KLRC2, human recombinant | 7353

NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant human KLRC2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

7353 | KLRC2 human recombinant DataSheet

Biomolecule/Target: KLRC2

Synonyms: NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C

Alternates names: NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C

Taglines: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules

NCBI Gene ID #: 24770

NCBI Gene Symbol: MCP1

Gene Source: Human

Accession #: P14844

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10-100 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 18.4 kDa (162 aa, 94-231 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 0.5 mg/ml

Appearance: Liquid

Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other buffered solutions and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A