KNG1 polyclonal Antibody | BS6646

KNG1 polyclonal Antibody | BS6646 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: In rats, four types of kininogens are produced, two of which are classical high and low molecular weight kininogens and two of which are low molecular weight-like kininogens, designated T-kininogen 1 and T-kininogen 2. T-kininogen 1 and T-kininogen 2 are 430 amino acid secreted rat proteins that each contain three cystatin domains and have nearly identical functions. Existing in plasma, both T-kininogen 1 and T-kininogen 2 are glycoproteins that act as thiol protease inhibitors and also play a role in blood coagulation, specifically by helping to optimally position blood coagulation factors. Additionally, T-kininogen 1 and T-kininogen 2 act as precursors of the active peptide Bradykinin and, as such, effect vascular permeability, hypotension and smooth muscle contraction.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KNG1 polyclonal Antibody detects endogenous levels of KNG1 protein.

Molecular Weight: Refer to figures

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BDK; Kininogen 1; KNG1; LMW; Low molecular weight growth promoting factor; Low molecular weight kininogen;

Immunogen: Recombinant full length Human KNG1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: