KPNA5 polyclonal Antibody | BS8839

KPNA5 polyclonal Antibody | BS8839 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs) . KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KPNA5 polyclonal Antibody detects endogenous levels of KPNA5 protein.

Molecular Weight: ~ 60kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Importin subunit alpha-6; Karyopherin subunit alpha-5; KPNA5

Immunogen: Recombinant full length Human KPNA5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Regulation of Microtubule Dynamics,Epigenetic Writers and Erasers of Histones H2A H2B and H4,