L-778123 hydrochloride | 9638

L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.

L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.

9638 | L-778123 hydrochloride DataSheet

Alternate Name/Synonyms: 4-((5-((4-(3-chlorophenyl)-3-oxopiperazin-1-yl)methyl)-1H-imidazol-1-yl)methyl)benzonitrile hydrochloride

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 253863-00-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₀ClN₅O

Molecular Weight: 405.88

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent FPTase and GGPTase-I inhibitor

MDL Number: N/A

PubChem CID: 216453

SMILES: C1CN(C(=O)CN1CC2=CN=CN2CC3=CC=C(C=C3)C#N)C4=CC(=CC=C4)Cl.Cl

InChi: InChI=1S/C22H20ClN5O.ClH/c23-19-2-1-3-20(10-19)28-9-8-26(15-22(28)29)14-21-12-25-16-27(21)13-18-6-4-17(11-24)5-7-18;/h1-7,10,12,16H,8-9,13-15H2;1H

InChi Key: YNBSQYGTJLIPJS-UHFFFAOYSA-N