LAG-3 Antibody [17B4] (ATTO 647N) | 36-113

LAG-3 Antibody [17B4] (ATTO 647N) | 36-113 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Research Area: Immunology, Innate Immunity

Tested Application: Flow, ICC

Application: Functional Application: Inhibition. Immunohistochemistry: (frozen sections (1:150) ) . Immunoprecipitation: (10ug/ml) . Western Blot: (5ug/ml) .

Specificiy: Recognizes human LAG-3.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: >95% (SDS-PAGE)

Clonality: Monoclonal

Clone: 17B4

Isotype: IgG1

Conjugate: ATTO 647N

Physical State: Liquid

Buffer: Liquid. In PBS containing 0.02% sodium azide.

Concentration: 1 mg/ml

Storage Condition: Keep conjugated formats at +4˚C. Stable for at least 1 year after receipt when stored at +4˚C.

Alternate Name: Lymphocyte Activation Gene-3; FDC Protein; CD223

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.