Laminin β1 polyclonal Antibody | BS90785

Laminin β1 polyclonal Antibody | BS90785 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB IHC FC

Application Range: WB:1:1,000 FC:1:50-1:100 IHC:1:100-1:500

Background: Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs) ) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of a, b, and g chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human Laminin b-1 gene maps to chromosome 7q22 and is ubiquitously expressed in tissues that produce basement membranes.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Laminin β1 polyclonal Antibody detects endogenous levels of Laminin β1 protein.

Molecular Weight: 198 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LAMB1, CLM, Cutis laxa with marfanoid phenotype, LAM B1, LAMB 1, LAMB1, LAMB1, Laminin B1, Laminin B1 chain, Laminin beta 1 chain, Laminin beta 1 chain precursor, Laminin beta1, Laminin subunit beta 1, Laminin subunit beta-1, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta, LIS5, MGC142015,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: