Laminin α-5 (N2402) polyclonal Antibody | BS9138

Laminin α-5 (N2402) polyclonal Antibody | BS9138 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: IHC

Application Range: IHC: 1:50~1:200

Background: Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs) ) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of α, β, and γ chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate laminin receptors.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Laminin α-5 (N2402) polyclonal Antibody detects endogenous levels of Laminin α-5 protein.

Molecular Weight: ~ 400 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LAMA5; Laminin alpha 5 chain; Laminin subunit alpha 5; Laminin subunit alpha-5; Laminin; alpha 5;

Immunogen: Synthetic peptide, corresponding to amino acids 2371-2420 of Human Laminin α-5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: