Lanatoside C | B2577

Lanatoside C is a cardiac glycoside, used in the treatment of congestive heart failure and cardiac arrhythmia. Lanatoside C suppresses colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair. Also activates IL-1β through activation of the inflammasome.

Lanatoside C is a cardiac glycoside, used in the treatment of congestive heart failure and cardiac arrhythmia. Lanatoside C suppresses colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair. Also activates IL-1β through activation of the inflammasome.

B2577 | Lanatoside C DataSheet

Alternate Name/Synonyms: Celadigal, Digilanide C, Celanid, [6-[6-[6-[[12,14-dihydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2-methyloxan-3-yl]oxy-2-methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-4-yl] acetate

Appearance: White solid

Formulation:

CAS Number: 17575-22-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₄₉H₇₆O₂₀

Molecular Weight: 985.12

Cell-Permeable?: True

Purity: ≥95% by TLC

Solubilities: ~ 2 mg/ml in Ethanol

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A cardiac glycoside

MDL Number: MFCD00869432

PubChem CID: 3879

SMILES: CC1C(C(CC(O1)OC2CCC3(C(C2)CCC4C3CC(C5(C4(CCC5C6=CC(=O)OC6)O)C)O)C)O)OC7CC(C(C(O7)C)OC8CC(C(C(O8)C)OC9C(C(C(C(O9)CO)O)O)O)OC(=O)C)O

InChi: InChI=1S/C49H76O20/c1-21-43(67-38-17-32(53)44(22(2)62-38)68-39-18-33(64-24(4)51)45(23(3)63-39)69-46-42(58)41(57)40(56)34(19-50)66-46)31(52)16-37(61-21)65-27-9-11-47(5)26(14-27)7-8-29-30(47)15-35(54)48(6)28(10-12-49(29,48)59)25-13-36(55)60-20-25/h13,21-23,26-35,37-46,50,52-54,56-59H,7-12,14-20H2,1-6H3

InChi Key: