LARP1 polyclonal Antibody | BS71974

LARP1 polyclonal Antibody | BS71974 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB

Application Range: WB 1:500 - 1:2000

Background: La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 β, 14-3-3 γ, 14-3-3 θ and 14-3-3 . Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LARP1 polyclonal Antibody detects endogenous levels of LARP1 protein.

Molecular Weight: 163kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LARP; La-related protein 1; KIAA0731

Immunogen: Recombinant Protein of human LARP1

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: