Latrunculin B | 2182

A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Less potent than Latrunculin A (Cat. No. 2181-100). May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies. Acts via a different mechanism than cytochalasins.

Latrunculin B is a cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin.

2182 | Latrunculin B DataSheet

Alternate Name/Synonyms: LAT-B; NSC 339663

Appearance: White to light yellow solid

Formulation: N/A

CAS Number: 76343-94-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₉NO₅S

Molecular Weight: 395.51

Cell-Permeable?: Yes

Purity: ≥ 95%

Solubilities: DMSO or EtOH

Handling: Protect from air and light

Country of Origin: USA

Tag Line: Actin polymerization inhibitor

MDL Number: MFCD00270879

PubChem CID: 56928133

SMILES: CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C

InChi: InChI=1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9+/t13-,15-,16-,17+,20-/m1/s1

InChi Key: NSHPHXHGRHSMIK-BNZYTJOMSA-N