LBR Antibody | 19-682

LBR Antibody | 19-682 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR (NP_002287.2) .

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: 22Rv1

Positive Control 2: Mouse eye

Positive Control 3: Mouse spleen

Positive Control 4: Mouse lung

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 68kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: C14SR, DHCR14B, LMN2R, PHA, PHASK, TDRD18, delta (14) -sterol reductase, 3-beta-hydroxysterol Delta (14) -reductase, C-14 sterol reductase, delta-14-SR, integral nuclear envelope inner membrane protein, sterol C14-reductase, tudor domain containing 18

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.