Leptin, Bovine Recombinant | P1594

A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores

P1594 | Leptin, Bovine Recombinant DataSheet

Biomolecule/Target :

Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor.

Alternates names: OB Protein, Obesity Protein, OBS, Obesity factor.

Taglines: Adipose-derived hormone which regulates energy intake & energy expenditure

NCBI Gene ID #: 280836

NCBI Gene Symbol: LEP

Gene Source: Bovine

Accession #: P50595

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: 0.95

Assay: SDS - PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method): Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 16 kDa.

Concentration:

Appearance: Lyophilized

Physical form description: Lyophilized from a concentrated (1mg/ml) solution with 0.0045 mM NaHCO3.

Reconstitution Instructions: It is recommended to reconstitute the lyophilized Leptin in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Amino acid sequence: Protein has146 amino acids. The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Arg.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans