LexA | LexA repressor | AS21 4541

LexA | LexA repressor | AS21 4541 | Gentaur UK, US & Europe Distribution

Immunogen: Full-size highly-purified recombinant LexA protein, UniProt: P0A7C2

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum. Contains 0.05% sodium azide.

Format: Liquid

Tested Application: Chromatin immunoprecipitation (ChIP), Immunolocalisation (IL), Western blot (WB)

Related Products: N/A

Recommended Dilutions: 1: 1000 - 1: 3000 (WB)

Molecular weight: 22, 3 | 23 kDa

Confirmed Reactivity: Escherichia coli

Predicted Reactivity: N/A

Not reactive in: N/A

Additional Information: N/A

Background: LexA represor binds specifically to the SOS-box sequence and represses the genes belonging to the SOS regulation. In response to DNA damage, RecA protein is activated by ss-DNA accumulated in the damaged cells and promotes autocleavage of LexA repressor by its coprotease activity. As a result, DNA repair genes and error prone polymerases are induced, and DNA damage is repaired and mutation is induced (1) . The lexA gene is used for yeast two-hybrid experiments as a bait to identify the protein-protein interaction in vivo.Alternative names: exrA, spr, tsl, umuA

Reconstitution: N/A

Storage: Store at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Bacteria

Research Area: Bacteria