Additional Information
Size: |
100 µg |
Target: |
LGR5 |
Conjugate: |
Dylight 488 |
Research Area: |
Cell Signaling | G Protein Signaling | GPCR | Stem Cells | Signaling Pathways | Wnt / Beta Catenin Pathway |
Alternative Name: |
GPR49 Antibody, G-protein coupled receptor 67 Antibody, G-protein coupled receptor HG38 Antibody, Leucine-rich repeat-containing G-protein coupled receptor 5 Antibody, LGR5 Antibody, G-protein coupled receptor 49 Antibody, GPR67 Antibody, GPCR GPR49 |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic peptide from the mid-protein of Human LGR5 (aa. 500-600) |
Immunogen Species: |
Human |
Applications: |
WB |
Host: |
Rabbit |
Isotype: |
N/A |
Species Reactivity: |
Human |
Antibody Dilution: |
WB (1:1000); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide |
Concentration: |
1 mg/ml |
Specificity: |
Detects 97 kDa. Band at ~97 kDa in isoform 2. Band at ~70 kDa is a degradation product.. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
A 1:1000 dilution of SPC-764 was sufficient for detection of LGR5 in 10 µg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody. |
Cellular Localization: |
Cell Membrane, Multi-Pass Membrane Protein, Golgi Apparatus, Trans-Golgi Network Membrane, Multi-Pass Membrane Protein |
Tissue Specificity: |
Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers |
Accession Number: |
NP_001264155.1 |
Gene ID: |
8549 |
Swiss-Prot: |
O75473 |
Field of Use: |
For in vitro research use only. |
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