LIMS2 Antibody | 14-859

LIMS2 Antibody | 14-859 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1) .

Research Area: Cell Cycle, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:1000

Specificiy: N/A

Positive Control 1: A-549

Positive Control 2: HeLa

Positive Control 3: Rat liver

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 39kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: LIMS2, PINCH2, OTTHUMP00000203866, OTTHUMP00000203850, OTTHUMP00000203848, LIM and senescent cell antigen-like domains 2, ILK-binding protein, FLJ10044

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase) , a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain forming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.