LJH685 | B1232

LJH685 is a potent and specific RSK (p90 ribosomal S6 kinase) inhibitor. Inhibits RSK1, 2, and 3 biochemical activities with IC₅₀ values of 4 to 13 nM.

LJH685 is a potent and specific RSK (p90 ribosomal S6 kinase) inhibitor. Inhibits RSK1, 2, and 3 biochemical activities with IC₅₀ values of 4 to 13 nM.

B1232 | LJH685 DataSheet

Alternate Name/Synonyms: 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-phenol

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1627710-50-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₁F₂N₃O

Molecular Weight: 381.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and specific RSK (p90 ribosomal S6 kinase) inhibitor

MDL Number: N/A

PubChem CID: 73010393

SMILES: CN1CCN(CC1)C2=CC=C(C=C2)C3=C(C=NC=C3)C4=CC(=C(C(=C4)F)O)F

InChi: InChI=1S/C22H21F2N3O/c1-26-8-10-27(11-9-26)17-4-2-15(3-5-17)18-6-7-25-14-19(18)16-12-20(23)22(28)21(24)13-16/h2-7,12-14,28H,8-11H2,1H3

InChi Key: IKUFKDGKRLMXEX-UHFFFAOYSA-N