LMNB2 polyclonal Antibody | BS90803

LMNB2 polyclonal Antibody | BS90803 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,mouse,rat

Application: WB ICC IHC

Application Range: WB:1:1,000-1:2,000 ICC:1:200 IHC:1:200

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Defects in LMNB2 are a cause of partial acquired lipodystrophy (APLD), which is a rare childhood disease characterized by loss of subcutaneous fat from the face and trunk.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: LMNB2 polyclonal Antibody detects endogenous levels of LMNB2 protein.

Molecular Weight: 68 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LMNB2, LAMB 2, LAMB2, Lamin-B2, LMN 2, LMN B2, LMN2, LMNB 2, LMNB2, LMNB2, MGC2721, RGD1563803,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: