LMO3 polyclonal Antibody | BS61533

LMO3 polyclonal Antibody | BS61533 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: LMO3 (LIM domain only 3), also known as RBTN3 (Rhombotin-3), RBTNL2 or RHOM3, is a 145 amino acid protein that contains two LIM zinc-binding domains and may be involved in transcriptional regulation events in tissues throughout the body. Aberrant expression of LMO3 is associated with the genesis and progression of human neuroblastoma, suggesting a role for LMO3 in oncogenesis. The gene encoding LMO3 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LMO3 polyclonal Antibody detects endogenous levels of LMO3 protein.

Molecular Weight: ~ 20 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LIM domain only protein 3; LMO-3; Neuronal-specific transcription factor DAT1; Rhombotin-3

Immunogen: Synthetic peptide, corresponding to amino acids 101-145 of Human LMO3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: