LOX Antibody (Center) [AMM02445G]

LOX Antibody (Center) [AMM02445G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H

Specificity: This LOX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.

Cellular Localisation: Secreted. Secreted, extracellular space

Molecular Weight: 46944

Clone: Monoclonal

Gene Name: LOX

Gene ID: 4015

Function: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:26838787) . Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity) .

Summary: Tissue Location: Heart, placenta, skeletal muscle, kidney, lung and pancreas.

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:500~1000

Synonyms: Protein-lysine 6-oxidase, Lysyl oxidase, LOX