LPGAT1 Antibody (Center) [APR17227G]

LPGAT1 Antibody (Center) [APR17227G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LPGAT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-177 amino acids from the Central region of human LPGAT1.

Cellular Localisation: Endoplasmic reticulum membrane; Multi-pass membrane protein

Molecular Weight: 43089

Clone: Polyclonal

Gene Name: LPGAT1 (HGNC:28985)

Gene ID: 9926

Function: Catalyzes the transfert of an acyl group from an acyl-CoA to a lysophosphatidylglycerol (LPG) leading to biosynthesis of phosphatidylglycerol, a precursor for cardiolipin synthesis (PubMed:15485873) . Uses various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl- CoAs and oleoyl-CoA as acyl donors (PubMed:15485873) . Prefers oleoyl- LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl- CoA as an acyl donor (PubMed:15485873) . In vitro can also catalyzes the transfert of an acyl group from an acyl-CoA to a monoacylglycerol leading to diacylglycerol synthesis, a precursor of triacylglycerol and plays a role in hepatic triacylglycerol synthesis and secretion (By similarity) . Prefers the sn-2-monoacylglycerol to rac-1- monoacylglycerol as acyl acceptor (By similarity) .

Summary: Tissue Location: Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Acyl-CoA:lysophosphatidylglycerol acyltransferase 1, 2.3.1.-, LPGAT1, FAM34A, KIAA0205