LPP Antibody (N-Term) [APR33378G]

LPP Antibody (N-Term) [APR33378G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This LPP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 32-66 amino acids from the human LPP.

Cellular Localisation: Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1

Molecular Weight: 65746

Clone: Polyclonal

Gene Name: LPP

Gene ID: 4026

Function: May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.

Summary: Tissue Location: Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP