Description
LRP6 Polyclonal Antibody | E-AB-17347 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, LDL receptor related protein 6, Low density lipoprotein receptor related protein 6, Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6, LRP6, OTTHUMP00000238979, OTTHUMP00000238980, OTTHUMP00000238982, STHAG7
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Signal transduction, Stem cells
Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Concentration: 1.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human LRP6
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:40-200, ELISA 1:2000-10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A