LBD
LRRC19 Antibody (C-term) [APR17240G]
- SKU:
- LBD-APR17240G
- Availability:
- Usually ships in 5 working days
Description
LRRC19 Antibody (C-term) [APR17240G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This LRRC19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the C-terminal region of human LRRC19.
Cellular Localisation: Membrane; Single-pass type I membrane protein
Molecular Weight: 42334
Clone: Polyclonal
Gene Name: LRRC19 (HGNC:23379)
Gene ID: 64922
Function: Pathogen-recognition receptor which mediates the activation of TRAF2- and TRAF6 NF-kappa-B signaling pathways and induces the expression of proinflammatory cytokines (PubMed:19679103, PubMed:25026888) . In kidney, prevents infection by uropathogenic bacteria by inducing the production of cytokines, chemokines and antimicrobial substances. In gut, involved in host-microbiota interactions, plays a critical role in promoting the recruitment of immune cells and intestinal inflammation (By similarity) .
Summary: Tissue Location: Expressed in renal collecting duct epithelial cells.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Leucine-rich repeat-containing protein 19, LRRC19