LRRFIP1 monoclonal Antibody | MB0034

LRRFIP1 monoclonal Antibody | MB0034 | Gentaur UK, US & Europe Distribution

Host: Mouse IgG1

Reactivity: Human,Mouse

Application: WB

Application Range: WB: 1:1000

Background: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins

Molecular Weight: Predicted band size:89KDa Observed band size:160KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GC-binding factor 2; TAR RNA-interacting protein; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1

Immunogen: Recombinant full length Human LRRFIP1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Notch Signaling,Nuclear Receptor Signaling,Cell Cycle Control G1 S Checkpoint,Epigenetic Writers and Erasers of Histone H3,Epigenetic Writers and Erasers of Histones H2A H2B and H4,