LRTOMT Antibody (N-term) [APR33001G]

LRTOMT Antibody (N-term) [APR33001G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LRTOMT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human LRTOMT.

Cellular Localisation: [Isoform 1]: Membrane; Single-pass membrane protein

Molecular Weight: 32155

Clone: Polyclonal

Gene Name: TOMT (HGNC:55527)

Gene ID: 220074

Function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity) . Required for auditory function (PubMed:18794526) . Component of the cochlear hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity (By similarity) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:4000

Synonyms: Transmembrane O-methyltransferase, Catechol O-methyltransferase 2, Protein LRTOMT2, LRTOMT, COMT2, TOMT