LRTOMT/LRRC51 Polyclonal Antibody | BS65814

LRTOMT/LRRC51 Polyclonal Antibody | BS65814 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,hu, mo, rat, dog

Application: WB,

Application Range: WB=1:500-2000

Background: This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR) -containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]

Storage & Stability: Store at 4°C short term. Aliquot and store at -13°C long term. Avoid freeze-thaw cycles.

Specificity: LRTOMT/LRRC51 Polyclonal Antibody detects endogenous levels of LRTOMT/LRRC51 protein.

Molecular Weight: ~26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.

Immunogen: KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51:1-100/192

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: