LSM4 polyclonal Antibody | BS8083

LSM4 polyclonal Antibody | BS8083 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IP

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:50 - 1:200

Background: Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease, Xm1.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LSM4 polyclonal Antibody detects endogenous levels of LSM4 protein.

Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: U6 snRNA-associated Sm-like protein LSm4; Glycine-rich protein; GRP; LSM4

Immunogen: Recombinant full length Human LSM4.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: