LTURM-34 | B2524

LTURM-34 is a potent DNA-PK inhibitor (IC₅₀ = 34 nM). Displays 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro.

LTURM-34 is a potent DNA-PK inhibitor (IC₅₀ = 34 nM). Displays 170-fold selectivity for DNA-PK over PI3-K. Attenuates proliferation of a wide range of tumor cell lines in vitro.

B2524 | LTURM-34 DataSheet

Alternate Name/Synonyms: 8-(4-Dibenzothienyll)-2-(4-morpholinyl)-4H-1,3-benzoxazin-4-one; LTURM34

Appearance: Off-white solid

Formulation:

CAS Number: 1879887-96-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₁₈N₂O₃S

Molecular Weight: 414.48

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >20 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent DNA-PK inhibitor

MDL Number:

PubChem CID: 122705987

SMILES: C1COCCN1C2=NC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56

InChi: InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2

InChi Key: SMMSWOMXOZLOPI-UHFFFAOYSA-N