LX-4211 | 9623

LX-4211 is a potent dual sodium-glucose cotransporter (SGLT)1 and SGLT2 inhibitor and an anti-diabetic agent. Sotagliflozin significantly improves glycemic control, without increasing the rate of hypoglycemia measurements, in diabetic mice maintained on a low insulin dose.

LX-4211 is a potent dual sodium-glucose cotransporter (SGLT)1 and SGLT2 inhibitor and an anti-diabetic agent. Sotagliflozin significantly improves glycemic control, without increasing the rate of hypoglycemia measurements, in diabetic mice maintained on a low insulin dose.

9623 | LX-4211 DataSheet

Alternate Name/Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol; Sotagliflozin

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1018899-04-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₅ClO₅S

Molecular Weight: 424.94

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent dual sodium-glucose cotransporter (SGLT)1 and SGLT2 inhibitor and an anti-diabetic agent.

MDL Number: N/A

PubChem CID: 24831714

SMILES: COC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)SC)O)O)O)Cl

InChi: InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1

InChi Key: QKDRXGFQVGOQKS-CRSSMBPESA-N