LXRα polyclonal Antibody | BS90813

LXRα polyclonal Antibody | BS90813 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC IHC FC

Application Range: WB:1:500 IHC:1：50-1：200 FC:1:50-1:100

Background: Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: LXRα polyclonal Antibody detects endogenous levels of LXRα protein.

Molecular Weight: 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NR1H3, LXRA, Liver X receptor alpha, LXR a, LXRA, NR1H3, NR1H3, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR alpha, Oxysterols receptor LXR-alpha, RLD 1, RLD1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: