LY-2795050 | B2351

LY-2795050 is a potent and selective κ-opioid Receptor (KOR) antagonist (IC₅₀ = 0.72 nM). Has the potential as a PET tracer to image KOR in vivo.

LY-2795050 is a potent and selective κ-opioid Receptor (KOR) antagonist (IC₅₀ = 0.72 nM). Has the potential as a PET tracer to image KOR in vivo.

B2351 | LY-2795050 DataSheet

Alternate Name/Synonyms: LY279050,(S)-3-chloro-4-(4-((2-(pyridin-3-yl)pyrrolidin-1-yl)methyl)phenoxy)benzamide

Appearance: Crystalline solid

Formulation:

CAS Number: 1346133-08-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₃H₂₂ClN₃O₂

Molecular Weight: 407.9

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: >50 mg/ml (DMSO) in 0

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A selective κ-opioid Receptor (KOR) antagonist

MDL Number:

PubChem CID: 56851583

SMILES: C1CC(N(C1)CC2=CC=C(C=C2)OC3=C(C=C(C=C3)C(=O)N)Cl)C4=CN=CC=C4

InChi: LOOCZNLSXJHWTG-NRFANRHFSA-N

InChi Key: InChI=1S/C23H22ClN3O2/c24-20-13-17(23(25)28)7-10-22(20)29-19-8-5-16(6-9-19)15-27-12-2-4-21(27)18-3-1-11-26-14-18/h1,3,5-11,13-14,21H,2,4,12,15H2,(H2,25,28)/t21-/m0/s1