A specific and cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 1.40 µM).LY 294002 is a specific and cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI...
PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2...