LY-310762 hydrochloride | B2190

LY-310762 is a potent antagonist of the serotonin (5-HT) receptor subtype 5-HT1D (Ki = 249 nM for guinea pig receptors). It is selective for 5-HT1D over the 5-HT1B receptor, where it inhibits binding of radiolabeled citalopram by only 32% when used at a concentration of 1,000 nM.

LY-310762 is a potent antagonist of the serotonin (5-HT) receptor subtype 5-HT1D (Ki = 249 nM for guinea pig receptors). It is selective for 5-HT1D over the 5-HT1B receptor, where it inhibits binding of radiolabeled citalopram by only 32% when used at a concentration of 1,000 nM.

B2190 | LY-310762 hydrochloride DataSheet

Alternate Name/Synonyms: 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 192927-92-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₄H₂₇FN₂O₂.HCl

Molecular Weight: 430.9

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent serotonin (5-HT) receptor subtype 5-HT1D antagonist

MDL Number: N/A

PubChem CID: 11957576

SMILES: CC1(C2=CC=CC=C2N(C1=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C.Cl

InChi: InChI=1S/C24H27FN2O2.ClH/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17;/h3-10,18H,11-16H2,1-2H3;1H

InChi Key: BOCLFQZPFYNVFD-UHFFFAOYSA-N