Description
Ly-6G Antibody [RB6-8C5] | 77-117 | Gentaur UK, US & Europe Distribution
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Innate Immunity
Tested Application: Flow, Func, IHC, IP
Application: N/A
Specificiy: The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) .
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clonality: Monoclonal
Clone: RB6-8C5
Isotype: Rat IgG2b, kappa
Conjugate: Unconjugated
Physical State: liquid
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: batch dependent
Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Alternate Name: Gr1, Gr-1, Ly-6G, Ly6g
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The RB6-8C5 monoclonal antibody reacts with the mouse Ly-6G (also known as Gr-1) . The Ly-6G protein is a myeloid differentiation antigen of 21-25 kDa, expressed in a regulated manner by the myeloid lineage in the bone marrow, where the level of antigen expression is correlated with the granulocyte maturation and differentiation. In the bone marrow, the antigen is not expressed by the erythroid cells. From the peripheric cells, RB6-8C5 binds with monocytes, neutrophils and eosinophils.As a marker for the mouse monocytes, macrophages and granulocytes, the RB6-8C5 antibody is usually combined with M1/70, a macrophage labeling antibody (Anti-CD11b) , for phenotypic analysis.